The GLI4 Polyclonal Antibody (PACO09480) is a valuable tool for research involving GLI4, a transcription factor involved in the Sonic Hedgehog signaling pathway. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in various applications, including Western blot and immunohistochemistry. GLI4 is a key regulator of cell growth, differentiation, and patterning during development, making it a critical target for research in developmental biology and cancer biology. By detecting and analyzing the expression of GLI4 in different cell types, researchers can gain insights into its role in various biological processes and diseases.
Furthermore, GLI4 has been implicated in the progression of certain types of cancer, including basal cell carcinoma and medulloblastoma. Understanding the function of GLI4 and its signaling pathway can provide valuable information for the development of targeted therapies for these cancers.Overall, the GLI4 Polyclonal Antibody is a powerful tool for studying the role of GLI4 in development, cancer, and other biological processes, advancing our understanding of these complex mechanisms and potentially leading to new therapeutic strategies.
GLI4: Belongs to the krueppel C2H2-type zinc-finger protein family.Protein type: C2H2-type zinc finger proteinChromosomal Location of Human Ortholog: 8q24.3Molecular Function: transcription factor activityBiological Process: regulation of transcription, DNA-dependent
