The Glypican-5 Polyclonal Antibody (CAB10411) is a powerful tool for researchers studying Glypican-5, a cell surface proteoglycan involved in various cellular signaling pathways. This antibody is produced in rabbits and has been extensively validated for its specificity in detecting Glypican-5 in human samples through Western blot analysis.Glypican-5 is known to play a role in cell growth, differentiation, and tissue morphogenesis, making it a key target for research in developmental biology, cancer biology, and tissue regeneration. By using the Glypican-5 Polyclonal Antibody, researchers can accurately detect and analyze the expression of Glypican-5 in different cell types, providing insights into its function and potential therapeutic applications.
The antibody's high reactivity and specificity for Glypican-5 make it an essential tool for investigating the molecular mechanisms underlying various cellular processes. Researchers studying cell signaling, tissue development, and disease pathology will find the Glypican-5 Polyclonal Antibody invaluable for their research endeavors.
Product Name:
GPC5 Rabbit Polyclonal Antibody
SKU:
CAB10411
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 320-550 of human GPC5 (NP_004457.1).
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.
Purification Method:
Affinity purification
Gene ID:
2262
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GPC5 antibody (CAB10411) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
