The GLYR1 Antibody (CAB9046) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications, including Western blotting.GlyR1 is essential for mediating inhibitory neurotransmission in the spinal cord and brainstem, making it a crucial target for studies related to neurological disorders, such as epilepsy, chronic pain, and movement disorders. By detecting and analyzing the expression of GlyR1 in different cell types, researchers can gain valuable insights into the mechanisms underlying these conditions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
GLYR1 Antibody
SKU:
CAB9046
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
NP60, NPAC, hNDF, BM045, HIBDL, N-PAC, GLYR1
Positive Sample:
HeLa, Mouse brain, Rat testis
Cellular Localization:
Nucleus.
Calculated MW:
61kDa
Observed MW:
60kDa
Enables DNA binding activity; methylated histone binding activity; and nucleosome binding activity. Involved in positive regulation of histone acetylation and positive regulation of transcription by RNA polymerase II. Located in cytosol and nucleoplasm. Part of nucleosome.
Purification Method
Affinity purification
Gene ID
84656
RRID
AB_2769625
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using GLYR1 Rabbit pAb (CAB9046) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s.
