The GPD1L Polyclonal Antibody (CAB14392) is a valuable tool for researchers studying the GPD1L protein, a key enzyme involved in glycerophospholipid metabolism. This antibody, produced in rabbits, exhibits high specificity and reactivity towards human samples, making it an ideal choice for Western blotting applications.GPD1L plays a crucial role in lipid metabolism, particularly in the production of phosphatidic acid, a key intermediate in lipid biosynthesis processes. Dysregulation of GPD1L has been linked to various metabolic disorders and cancer progression, making it a promising target for therapeutic interventions.
By using the GPD1L Polyclonal Antibody, researchers can detect and analyze GPD1L protein levels in different cell types and tissues, providing valuable insights into its function and potential implications in disease development. This antibody is a valuable tool for studies in metabolism, cancer research, and drug discovery aimed at targeting lipid metabolism pathways.
Product Name:
GPD1L Rabbit Polyclonal Antibody
SKU:
CAB14392
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-351 of human GPD1L (NP_055956.1).
The protein encoded by this gene catalyzes the conversion of sn-glycerol 3-phosphate to glycerone phosphate. The encoded protein is found in the cytoplasm, associated with the plasma membrane, where it binds the sodium channel, voltage-gated, type V, alpha subunit (SCN5A). Defects in this gene are a cause of Brugada syndrome type 2 (BRS2) as well as sudden infant death syndrome (SIDS).
Purification Method:
Affinity purification
Gene ID:
23171
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using GPD1L Rabbit pAb (CAB14392) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
