The GPR6 Antibody (CAB14738) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the GPR6 protein, this antibody enables accurate detection and analysis in various cell types, making it ideal for studies in neuroscience and immunology research.GPR6 is known for its role in modulating neurotransmitter release and synaptic transmission, making it a potential target for therapeutic interventions in conditions such as Parkinson's disease and drug addiction.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
GPR6 Antibody
SKU:
CAB14738
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
GPR6
Positive Sample:
U-251MG
Cellular Localization:
Cell Membrane, Multi-Pass Membrane Protein.
Calculated MW:
38kDa
Observed MW:
38kDa
Predicted to enable sphingosine-1-phosphate receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and regulation of metabolic process. Predicted to act upstream of or within positive regulation of cytosolic calcium ion concentration. Predicted to be integral component of plasma membrane. Predicted to be active in cytoplasm and plasma membrane.
Purification Method
Affinity purification
Gene ID
2830
RRID
AB_2761616
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from U-251MG cells, using GPR6 Rabbit pAb (CAB14738) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.