The GPRC6A Antibody (CAB8525) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, demonstrates high specificity for human samples and has been validated for use in Western blotting applications.GPRC6A is gaining attention for its potential role in metabolic disorders, including diabetes and obesity, as well as in bone health. By targeting this receptor, researchers can better understand its signaling pathways and potential therapeutic implications in these disease states.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
GPRC6A Antibody
SKU:
CAB8525
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
GPCR, bA86F4.3, GPRC6A
Positive Sample:
293T, Mouse lung, Mouse liver, Mouse spleen, Rat lung
Cellular Localization:
Cell Membrane, Multi-Pass Membrane Protein.
Calculated MW:
105kDa
Observed MW:
105kDa
Members of family C of the G protein-coupled receptor (GPCR) superfamily, such as GPRC6A, are characterized by an evolutionarily conserved amino acid-sensing motif linked to an intramembranous 7-transmembrane loop region. Several members of GPCR family C, including GPRC6A, also have a long N-terminal domain (summary by Pi et al., 2005 [PubMed 16199532]).
Purification Method
Affinity purification
Gene ID
222545
RRID
AB_2769673
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using GPRC6A Rabbit pAb (CAB8525) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
