The GPVI/GP6 Polyclonal Antibody (CAB24524) is a high-quality antibody developed for reliable detection and analysis of target proteins. Enables collagen binding activity and collagen receptor activity. Involved in vasculature development. Acts upstream of or within collagen-activated tyrosine kinase receptor signaling pathway. Is integral component of plasma membrane. Is expressed in bone marrow; femur; liver; and spleen. Human ortholog(s) of this gene implicated in platelet-type bleeding disorder 11. Orthologous to human GP6 (glycoprotein VI platelet).
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
GPVI/GP6 Polyclonal Antibody
SKU:
CAB24524
Size:
100μL, 20μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:1000 - 1:5000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
Gpvi, Gm469, 9830166G18Rik, GPVI/GP6
Positive Sample:
Human plasma
Calculated MW:
34kDa
Observed MW:
60kDa
Enables collagen binding activity and collagen receptor activity. Involved in vasculature development. Acts upstream of or within collagen-activated tyrosine kinase receptor signaling pathway. Is integral component of plasma membrane. Is expressed in bone marrow; femur; liver; and spleen. Human ortholog(s) of this gene implicated in platelet-type bleeding disorder 11. Orthologous to human GP6 (glycoprotein VI platelet).
Purification Method
Affinity purification
Gene ID
243816
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from Human plasma, using GPVI/GP6 Rabbit pAb (CAB24524) at 1:2000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
