The NDUFA13/GRIM19 Monoclonal Antibody (CAB3782) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated using rabbit monoclonal technology, exhibits high specificity and sensitivity in detecting GRIM19 in various types of samples, particularly human tissues.GRIM19, also known as Gene associated with Retinoid-Interferon-induced Mortality 19, is a key player in the intricate network of cellular pathways that control cell death and survival. Dysregulation of GRIM19 has been implicated in a variety of diseases, including cancer and neurodegenerative disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
NDUFA13/GRIM19 Monoclonal Antibody
SKU:
CAB3782
Size:
20μL, 100μL
Reactivity:
Human
Clone Number:
ARC0833
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
This gene encodes a subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain. The protein is required for complex I assembly and electron transfer activity. The protein binds the signal transducers and activators of transcription 3 (STAT3) transcription factor, and can function as a tumor suppressor. The human protein purified from mitochondria migrates at approximately 16 kDa. Transcripts originating from an upstream promoter and capable of expressing a protein with a longer N-terminus have been found, but their biological validity has not been determined.
Purification Method
Affinity purification
Gene ID
51079
RRID
AB_2863140
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using NDUFA13/NDUFA13/GRIM19 Rabbit mAb (CAB3782) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
