The Gsdmc3 Polyclonal Antibody (CAB16741) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the GSDMC3 protein, this antibody allows for the detection and analysis of GSDMC3 in a variety of cell types, making it an excellent choice for studies in cell biology, apoptosis, and cancer research.GSDMC3, also known as Gasdermin C3, is involved in programmed cell death processes, including pyroptosis and apoptosis.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse samples.
Product Name:
Gsdmc3 Polyclonal Antibody
SKU:
CAB16741
Size:
20μL, 100μL
Reactivity:
Mouse
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
9930109F21Rik, Gsdmc3
Positive Sample:
Mouse spleen, Mouse brain
Cellular Localization:
Cytoplasm.
Calculated MW:
54kDa
Observed MW:
54kDa
Predicted to enable phosphatidylinositol-4,5-bisphosphate binding activity; phosphatidylinositol-4-phosphate binding activity; and phosphatidylserine binding activity. Predicted to be involved in defense response to bacterium and pyroptosis. Predicted to act upstream of or within programmed cell death. Predicted to be located in cytoplasm. Is expressed in gut and metanephros. Orthologous to human GSDMC (gasdermin C).
Purification Method
Affinity purification
Gene ID
270328
RRID
AB_2769696
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using Gsdmc3 Rabbit pAb (CAB16741) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
