The GTF2IRD1 Antibody (CAB6613) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By binding to the GTF2IRD1 protein, this antibody allows for the detection and analysis of GTF2IRD1 levels in various cell types, making it an essential reagent for studies in gene regulation and developmental biology.GTF2IRD1 plays a crucial role in controlling the expression of genes involved in development and differentiation processes.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
GTF2IRD1 Antibody
SKU:
CAB6613
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
293T, HeLa, BT-474, SW480, Mouse ovary, Mouse thymus, Rat kidney, Rat liver
Cellular Localization:
Nucleus.
Calculated MW:
106kDa
Observed MW:
106kDa
The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
9569
RRID
AB_2767203
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using GTF2IRD1 Rabbit pAb (CAB6613) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 5min.
