The H2-Aa Antibody (CAB18325) is a high-quality antibody developed for reliable detection and analysis of target proteins. This rabbit-derived antibody boasts high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the H2-AA protein, researchers can confidently detect and analyze its expression in various cell types, making it an essential tool for studies in immunology and infectious disease research.H2-AA is a critical component of the major histocompatibility complex (MHC) class II molecule, playing a crucial role in presenting antigens to T cells and eliciting immune responses.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
H2-Aa Antibody
SKU:
CAB18325
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
External Side Of Plasma Membrane, Lysosome, Plasma Membrane.
Calculated MW:
28kDa
Observed MW:
28kDa
Enables peptide antigen binding activity. Involved in response to interferon-gamma. Acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II and positive regulation of T cell differentiation. Located in external side of plasma membrane and lysosome. Part of MHC class II protein complex. Is expressed in central nervous system; retina; and thymus primordium. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); gastrointestinal system cancer (multiple); glomerulonephritis (multiple); hematologic cancer (multiple); and systemic scleroderma (multiple). Orthologous to several human genes including HLA-DQA1 (major histocompatibility complex, class II, DQ alpha 1).
Purification Method
Affinity purification
Gene ID
14960
RRID
AB_2862097
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using H2-Aa Rabbit pAb (CAB18325) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
