The HABP2 Polyclonal Antibody (CAB6919) is a crucial tool for researchers studying the HABP2 protein, which is involved in various cellular processes, including blood coagulation and inflammation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the HABP2 protein, researchers can detect and analyze its expression in different cell types, making it a valuable tool for studies in cardiovascular disease, thrombosis, and inflammation research.HABP2, also known as hyaluronan-binding protein 2 or factor VII-activating protease, is a key player in blood clotting and inflammatory pathways.
Dysregulation of HABP2 has been implicated in various diseases, including thrombosis, atherosclerosis, and inflammation-related disorders. Understanding the function of HABP2 is essential for developing targeted therapies and diagnostic tools for these conditions.By utilizing the HABP2 Polyclonal Antibody, researchers can gain valuable insights into the role of HABP2 in health and disease, paving the way for novel treatments and diagnostic approaches in cardiovascular and inflammatory conditions.
Product Name:
HABP2 Rabbit Polyclonal Antibody
SKU:
CAB6919
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-313 of human HABP2 (NP_004123.1).
This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by hepatocytes and proteolytically processed to generate heavy and light chains that form the mature heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This extracellular protease binds hyaluronic acid and may play a role in the coagulation and fibrinolysis systems. Mutations in this gene are associated with nonmedullary thyroid cancer and susceptibility to venous thromboembolism. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
Purification Method:
Affinity purification
Gene ID:
3026
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of MCF7 cells using HABP2 Rabbit pAb (CAB6919). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
