The HBQ1 Polyclonal Antibody (PACO27333) is a valuable tool for researchers studying the HBQ1 protein, which is involved in immune regulation and the inhibition of immune responses. This high-quality antibody, produced in rabbits, is specifically reactive with human samples and has been validated for use in Western blot applications.HBQ1, also known as an immune regulatory molecule, plays a crucial role in modulating immune responses and maintaining immune homeostasis. Its involvement in immune regulation makes it a promising target for research into various diseases, including cancer, autoimmune disorders, and chronic inflammatory conditions.
Understanding the function of HBQ1 is essential for the development of targeted therapies that manipulate immune function in these disease contexts.The HBQ1 Polyclonal Antibody enables the detection and analysis of HBQ1 protein in different cell types, making it an excellent tool for studies in immunology and cancer research. Researchers can utilize this antibody to further explore the role of HBQ1 in immune regulation and its potential implications for disease therapy.
Antibody Name:
HBQ1 Antibody (PACO27333)
Antibody SKU:
PACO27333
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Human
Immunogen:
Recombinant Human Hemoglobin subunit theta-1 protein (1-142AA)
HBQ1: Theta-globin mRNA is found in human fetal erythroid tissue but not in adult erythroid or other nonerythroid tissue. The theta-1 gene may be expressed very early in embryonic life, perhaps sometime before 5 weeks. Theta-1 is a member of the human alpha-globin gene cluster that involves five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-2 -pseudoalpha-1 - alpha-2 - alpha-1 - theta-1 - 3'. Research supports a transcriptionally active role for the gene and a functional role for the peptide in specific cells, possibly those of early erythroid tissue. [provided by RefSeq, Jul 2008]Chromosomal Location of Human Ortholog: 16p13.3Cellular Component: hemoglobin complexMolecular Function: iron ion binding; heme binding; oxygen binding; oxygen transporter activityBiological Process: oxygen transport
UniProt Protein Details:
NCBI Summary:
Theta-globin mRNA is found in human fetal erythroid tissue but not in adult erythroid or other nonerythroid tissue. The theta-1 gene may be expressed very early in embryonic life, perhaps sometime before 5 weeks. Theta-1 is a member of the human alpha-globin gene cluster that involves five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-2 -pseudoalpha-1 - alpha-2 - alpha-1 - theta-1 - 3'. Research supports a transcriptionally active role for the gene and a functional role for the peptide in specific cells, possibly those of early erythroid tissue. [provided by RefSeq, Jul 2008]
