The Heme Oxygenase-1 (HO-1/HMOX1) Polyclonal Antibody is a valuable tool for researchers studying the role of HO-1 in various biological processes. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot and immunohistochemistry applications.HO-1, a stress-response enzyme, is known for its cytoprotective and anti-inflammatory properties. It plays a crucial role in heme metabolism and has been implicated in various diseases, including cancer, cardiovascular diseases, and neurodegenerative disorders. By targeting the HO-1 protein, researchers can gain insights into the mechanisms underlying these diseases and develop novel therapeutic strategies.
This antibody offers researchers a reliable tool for detecting and analyzing the expression of HO-1 in different cell types and tissues. Its high specificity and sensitivity make it an ideal choice for studies in immunology, cancer research, and oxidative stress-related conditions. By understanding the function of HO-1, researchers can pave the way for the development of targeted therapies aimed at modulating its activity for therapeutic benefit.
Product Name:
Heme Oxygenase 1 (HO-1/HMOX1) Polyclonal Antibody
SKU:
CAB21452
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-288 of human Heme Oxygenase 1 (HO-1/HMOX1) (NP_002124.1).
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family.
Purification Method:
Affinity purification
Gene ID:
3162
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of HeLa cells, using Heme Oxygenase 1 (HO-1/HMOX1) antibody (CAB21452) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
