The HIPK4 Antibody (PACO00906) is a high-quality polyclonal antibody designed for research involving the homeodomain-interacting protein kinase 4 (HIPK4). HIPK4 is a protein kinase that plays a crucial role in various cellular processes, including cell proliferation, differentiation, and apoptosis. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. It specifically binds to the HIPK4 protein, enabling researchers to detect and analyze its expression in different cell types.
HIPK4 has been implicated in multiple pathways related to cancer, development, and immune response, making it a valuable target for studies in oncology, developmental biology, and immunology. Understanding the function and regulation of HIPK4 is essential for unraveling its role in various cellular processes and diseases. Overall, the HIPK4 Antibody (PACO00906) is a reliable tool for researchers looking to explore the biological functions of HIPK4 and its potential implications in cancer and other diseases.
Antibody Name:
HIPK4 Antibody
Antibody SKU:
PACO00906
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC, IF
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000
Species Reactivity:
Human, Mouse, Rat
Immunogen:
synthesized peptide derived from the C-terminal region of human HIPK4.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
HIPK4; Homeodomain-interacting protein kinase 4
UniProt Protein Function:
HIPK4: a CMGC kinase of the DYRK family.Protein type: EC 2.7.11.1; Protein kinase, CMGC; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); CMGC group; DYRK family; HIPK subfamilyChromosomal Location of Human Ortholog: 19q13.2Molecular Function: protein binding
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the homeodomain interacting protein kinase (HIPK) family of proteins. While other members of this family are found throughout vertebrates, this member is present only in mammals. Compared to other members of this family, the encoded protein lacks a nuclear localization signal and a C-terminal autoinhibitory domain. The encoded protein exhibits kinase activity and may phosphorylate the tumor suppressor protein p53. [provided by RefSeq, Jul 2016]
