Description
system_update_altDatasheet
| Product Name: | HLA-DR monoclonal antibody (PE) |
| Product Code: | AGIM0146 |
| Size: | 500 µL |
| Reactivity: | Human |
| Clone: | LT-DR |
| Applications: | Flow Cytometry |
| Conjugate: | PE |
| Isotype: | IgG2a |
| Host Species: | Mouse |
| Storage: | Store at 4°C. Do not freeze. Avoid prolonged exposure to light |
| Background: | HLA-DR is a transmembrane human major histocompatibility complex 2 (MHC II) family member and consists of a 34 kDa (alpha) subunit and one of several 28 kDa (beta) subunits. HLA-Dr is expressed primarily on B cells on which it presents antigenic peptides for recognition by the T cell receptor on CD4+T cells. This interaction is central to antigen specificity in the adaptive immune response. HLA-DR alleles, polymorphisms and aberrant expression are linked to a variety of diseases including autoimmunity and cancer. |
