The [KO Validated] CD168/RHAMM Monoclonal Antibody (CAB11666) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been rigorously validated for use in Western blot applications. By binding to the CD168 protein, researchers can effectively detect and analyze this molecule in a variety of cell types, making it an ideal choice for studies in immunology and cancer research.CD168, also referred to as an immune inhibitory receptor, plays a crucial role in immune homeostasis by modulating inflammation and suppressing allergic responses. Its involvement in immune response modulation highlights its significance as a target for research in diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
[KO Validated] CD168/RHAMM Monoclonal Antibody
SKU:
CAB11666
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Clone Number:
ARC0667
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
CD168, IHABP, RHAMM, CD168/RHAMM
Positive Sample:
K-562
Cellular Localization:
Cell Surface, Cytoplasm.
Calculated MW:
84kDa
Observed MW:
84kDa
The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Purification Method
Affinity purification
Gene ID
3161
RRID
AB_2861623
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from K-562 cells, using CD168/RHAMM Rabbit mAb (CAB11666) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
Immunohistochemistry analysis of paraffin-embedded Mouse kidney using CD168/RHAMM Rabbit mAb (CAB11666) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
