The HOXD10 Monoclonal Antibody (CAB23992) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced using advanced technology, specifically targets the HOXD10 protein and is highly specific for human samples. HOXD10 is a critical transcription factor that regulates gene expression and plays a vital role in the development of various tissues and organs. Dysregulation of HOXD10 has been linked to cancer progression and metastasis, making it a promising target for cancer therapy research.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse samples.
Product Name:
HOXD10 Monoclonal Antibody
SKU:
CAB23992
Size:
20μL, 100μL
Reactivity:
Mouse
Clone Number:
ARC62112
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
HOX4, HOX4D, HOX4E, Hox-4.4, HOXD10
Positive Sample:
Mouse kidney
Cellular Localization:
Nucleus.
Calculated MW:
38kDa
Observed MW:
38kDa
This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease.
Purification Method
Affinity purification
Gene ID
3236
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from Mouse kidney, using HOXD10 Rabbit mAb (CAB23992) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
