The HRPT2 / CDC73 Monoclonal Antibody (CAB23565) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced using advanced monoclonal antibody technology, has high specificity and sensitivity for HRPT2/CDC73 in a variety of experimental settings.The HRPT2/CDC73 protein is known to be a tumor suppressor gene, with mutations or dysregulation linked to various cancers, particularly parathyroid tumors. By targeting HRPT2/CDC73 with this monoclonal antibody, researchers can accurately detect and measure levels of the protein in cell lysates, tissue samples, and other experimental systems.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
HRPT2 / CDC73 Monoclonal Antibody
SKU:
CAB23565
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC3131
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.
Purification Method
Affinity purification
Gene ID
79577
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using HRPT2 / CDC73 Rabbit mAb (CAB23565) at 1:800 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
