The HSD17B2 Antibody (CAB1983) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the HSD17B2 protein, this antibody allows for the detection and analysis of this important enzyme in a variety of cell types.HSD17B2, also known as 17-beta-hydroxysteroid dehydrogenase type 2, plays a crucial role in the biosynthesis and inactivation of steroid hormones, making it a potential target for therapeutic interventions in hormone-related conditions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
HSD17B2 Antibody
SKU:
CAB1983
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
HSD17, SDR9C2, EDH17B2, HSD17B2
Positive Sample:
Mouse liver, Rat liver
Cellular Localization:
Membrane, Single-Pass Type Ii Membrane Protein.
Calculated MW:
43kDa
Observed MW:
35-40kDa
Enables estradiol 17-beta-dehydrogenase activity and testosterone dehydrogenase (NAD+) activity. Involved in response to retinoic acid. Predicted to be located in endoplasmic reticulum membrane.
Purification Method
Affinity purification
Gene ID
3294
RRID
AB_2764009
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using HSD17B2 Rabbit pAb (CAB1983) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 0.1s.
