The HSP90AA1 Polyclonal Antibody is specifically designed for research involving the heat shock protein 90 alpha family class A member 1 (HSP90AA1). This cell surface molecule is known to play a critical role in protein folding, cell signaling, and cell cycle control. The antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blotting applications.HSP90AA1 is a key chaperone protein that assists in the folding and stabilization of numerous client proteins involved in various cellular processes. Dysregulation of HSP90AA1 has been linked to a range of diseases, including cancer, neurodegenerative disorders, and infectious diseases.
By targeting HSP90AA1, researchers can gain insights into its function and potential therapeutic applications in these disease contexts.This antibody binds specifically to HSP90AA1, allowing for precise detection and analysis of the protein in different cell types. Its versatility and reliability make it an ideal tool for studies in molecular biology, cell biology, and disease mechanisms. By understanding the role of HSP90AA1, researchers can uncover novel pathways for targeted therapies and drug development.
The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3320
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using HSP90AA1 Rabbit pAb (CAB23880) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
