The HSPA4 Polyclonal Antibody is an essential tool for researchers studying the HSPA4 protein, a heat shock protein involved in cellular stress response and protein folding. This high-quality antibody, produced in rabbits, has been validated for use in Western blot applications and is highly reactive with human samples.HSPA4, also known as HSP70, plays a crucial role in maintaining protein homeostasis under stressful conditions, such as heat shock or oxidative stress. Its diverse functions make it a key player in various cellular processes, including protein folding, stabilization, and degradation.
By utilizing the HSPA4 Polyclonal Antibody, researchers can accurately detect and analyze the expression levels of HSPA4 in different cell types, providing valuable insights into its role in cellular physiology and pathology. This antibody is particularly useful for studies in molecular biology, cell biology, and cancer research, where understanding the function of HSPA4 may lead to the development of novel therapeutic strategies targeting protein misfolding diseases.
Product Name:
HSPA4 Polyclonal Antibody
SKU:
CAB22022
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 680-840 of human HSPA4 (NP_002145.3).
Predicted to enable ATP binding activity. Involved in chaperone-mediated protein complex assembly and protein insertion into mitochondrial outer membrane. Located in cytosol and extracellular exosome. Implicated in Chagas disease. Biomarker of chronic obstructive pulmonary disease; rheumatoid arthritis; type 2 diabetes mellitus; and ulcerative colitis.
Purification Method:
Affinity purification
Gene ID:
3308
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using HSPA4 antibody (CAB22022) at 1:800 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
