The HTR3C Polyclonal Antibody (PAC015798) is a valuable tool for researchers studying the HTR3C protein, a serotonin receptor that plays a key role in neuronal signaling and gastrointestinal function. This antibody, raised in rabbits, specifically targets the HTR3C protein and is highly reactive with human samples. It has been validated for use in Western blot applications, enabling accurate detection and analysis of HTR3C in various cell types.HTR3C is a promising target for research in neurology, gastroenterology, and pharmacology, as it is involved in the regulation of serotonin signaling in the brain and gut.
By understanding the function and expression of HTR3C, researchers can uncover new insights into the mechanisms of neurological disorders, gastrointestinal diseases, and psychiatric conditions. The HTR3C Polyclonal Antibody provides a reliable tool for investigating the role of HTR3C in these important areas of study.
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO15798(HTR3C Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Mouse muscle tissue, HT29 cells, Primary antibody: PACO15798(HTR3C Antibody) at dilution 1/650, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds.
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15798(HTR3C Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
Background:
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit C of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3.
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit C of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. [provided by RefSeq, Jul 2008]
