The HTR3D Polyclonal Antibody (PACO02643) is a valuable tool for researchers studying the HTR3D protein, a key player in serotonin signaling pathways and psychiatric disorders. This antibody is produced by immunizing rabbits and has been validated for use in Western blot applications with high reactivity towards human samples.The HTR3D protein belongs to the serotonin-gated ion channel receptor family and is involved in regulating neurotransmission in the central nervous system. Dysregulation of serotonin signaling has been linked to a variety of psychiatric disorders, making HTR3D an important target for therapeutic interventions.
By using the HTR3D Polyclonal Antibody, researchers can accurately detect and analyze HTR3D expression in various cell types, allowing for a better understanding of its role in serotonin signaling and its potential implications for psychiatric diseases. This antibody is suitable for studies in neurobiology, pharmacology, and drug development, providing valuable insights into the molecular mechanisms underlying psychiatric disorders.
Antibody Name:
HTR3D Antibody
Antibody SKU:
PACO02643
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the N-terminal region of human SR-3D.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
HTR3D; 5-hydroxytryptamine receptor 3D; 5-HT3-D; 5-HT3D; Serotonin receptor 3D
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
The protein encoded this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit D of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a mitogen and a hormone. This hormone has been linked to neuropsychiatric disorders, including anxiety, depression, and migraine. Serotonin receptors causes fast and depolarizing responses in neurons following activation. The genes encoding subunits C, D and E of this type 3 receptor form a cluster on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]
