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Biotin Anti-Human CD11a Antibody [TS1/22.1.1.13] (AGEL0234)

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SKU AGEL0234
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Human
Host Species Mouse
Isotype IgG1
Clone TS1/22.1.1.13
Conjugation Biotin
Applications FC
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Description

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Biotin Anti-Human CD11a Antibody [TS1/22.1.1.13]

The Human CD11a Monoclonal Antibody (Biotin Conjugated, TS1/22) is a specialized tool for researchers studying CD11a, a cell surface protein known for its role in immune cell adhesion and activation. This monoclonal antibody, conjugated with biotin for enhanced detection capabilities, is meticulously designed and validated for use in a variety of experimental applications.CD11a, a member of the integrin family, plays a pivotal role in mediating cell-cell interactions, particularly in the context of immune responses. By targeting and binding specifically to CD11a, this antibody enables precise detection and analysis of this crucial protein in human samples. Researchers can utilize this antibody in techniques such as flow cytometry, immunofluorescence, and immunoprecipitation to explore the functions and expression patterns of CD11a in different cell types and experimental conditions.

Studying CD11a is essential for unraveling the mechanisms behind immune cell activation, migration, and signaling, making this antibody a valuable asset for investigations in immunology, inflammation, and autoimmune diseases. Its high specificity and reactivity make it an indispensable tool for researchers seeking to delve deeper into the intricate pathways governed by CD11a and its impact on immune system regulation and function.

Product Title:Biotin Anti-Human CD11a Antibody [TS1/22.1.1.13]
SKU:AGEL0234
Size:25µg, 100µg
Clone No:TS1/22.1.1.13
Synonyms:Integrin alpha-L;Itgal;CD11 antigen-like family member A;LFA-1A;Lymphocyte antigen 15;Ly-15;CD11a;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Biotin Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P20701
Gene ID:3683
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

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