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PE Anti-Human CD11c Antibody [BU15] (AGEL0447)

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SKU AGEL0447
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Human
Host Species Mouse
Isotype IgG1
Clone BU15
Conjugation PE
Applications FC
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Description

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PE Anti-Human CD11c Antibody [BU15]

The Human CD11c Monoclonal Antibody PE-Conjugated (BU15) is a powerful tool for research involving CD11c, a key cell surface marker expressed on dendritic cells. This antibody, conjugated to phycoerythrin (PE), allows for easy detection and analysis of CD11c in human samples, making it an essential reagent for immunology and cell biology studies.CD11c is a well-known marker for dendritic cells, which play a crucial role in the immune system by presenting antigens to T-cells and initiating immune responses. By targeting CD11c with this monoclonal antibody, researchers can accurately identify and study dendritic cells in various experimental setups, from flow cytometry to immunofluorescence assays.

The use of this PE-conjugated CD11c monoclonal antibody provides researchers with a reliable tool to investigate the role of dendritic cells in immune responses, inflammatory processes, and disease pathogenesis. Its specificity and sensitivity make it a valuable asset for those studying dendritic cell biology, vaccine development, and immunotherapy strategies. Trust in the BU15 antibody to enhance your research and unlock new insights into the intricate world of dendritic cell biology.

Product Title:PE Anti-Human CD11c Antibody [BU15]
SKU:AGEL0447
Size:20 Tests, 100 Tests, 200 Tests
Clone No:BU15
Synonyms:Integrin alpha-X;Itgax;CD11 antigen-like family member C;Leukocyte adhesion receptor p150+95;CD11c;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P20702
Gene ID:3687
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11c is a 145-150 kD type I transmembrane glycoprotein also known as integrin αX and CR4. CD11c non-covalently associates with integrin β2 (CD18) and is expressed on monocytes/macrophages, dendritic cells, granulocytes, NK cells, and subsets of T and B cells. CD11c has been reported to play a role in adhesion and CTL killing through its interactions with fibrinogen, CD54, and iC3b.

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