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PE/Cyanine7 Anti-Human CD11c Antibody [BU15] (AGEL1461)

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SKU AGEL1461
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Human
Host Species Mouse
Isotype IgG2a,k
Clone BU15
Conjugation PE/Cy7
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Description

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PE/Cyanine7 Anti-Human CD11c Antibody [BU15]

The Human CD11c Monoclonal Antibody PE-Cyanine7 Conjugated (BU15) is an essential tool for researchers studying the CD11c protein, a key marker of dendritic cells and other immune cell populations. Specifically conjugated for flow cytometry applications, this antibody is engineered for high sensitivity and specificity when detecting human CD11c in samples.CD11c is a critical cell surface molecule involved in antigen presentation, immune response regulation, and inflammatory processes. By targeting CD11c, researchers can gain insights into the function of dendritic cells, their role in adaptive immunity, and their involvement in various disease states such as infections, autoimmune disorders, and cancer.

With its fluorescence detection capabilities, this conjugated CD11c antibody offers a reliable method for analyzing and sorting CD11c-expressing cells in complex biological samples. Its versatility and sensitivity make it an invaluable tool for immunologists, oncologists, and researchers interested in the intricate workings of the immune system.

Product Title:PE/Cyanine7 Anti-Human CD11c Antibody [BU15]
SKU:AGEL1461
Size:20 Tests, 100 Tests, 200 Tests
Clone No:BU15
Synonyms:Integrin alpha-X;Itgax;CD11 antigen-like family member C;Leukocyte adhesion receptor p150+95;CD11c;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE/Cyanine7 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P20702
Gene ID:3687
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11c is a 145-150 kD type I transmembrane glycoprotein also known as integrin αX and CR4. CD11c non-covalently associates with integrin β2 (CD18) and is expressed on monocytes/macrophages, dendritic cells, granulocytes, NK cells, and subsets of T and B cells. CD11c has been reported to play a role in adhesion and CTL killing through its interactions with fibrinogen, CD54, and iC3b.

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