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Key Features

Biotin Anti-Human CD18 Antibody [TS1/18.1.2.11] (AGEL0240)

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SKU AGEL0240
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Human
Host Species Mouse
Isotype IgG1
Clone TS1/18.1.2.11
Conjugation Biotin
Applications FC
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Description

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Biotin Anti-Human CD18 Antibody [TS1/18.1.2.11]

The Human CD18 Monoclonal Antibody (Biotin Conjugated) TS1/18, 1/2/11 (AGEL0240) is a specialized tool for researchers investigating CD18, a crucial cell adhesion molecule involved in immune responses. This monoclonal antibody, conjugated with biotin for enhanced detection, is specifically designed for use with human samples. CD18, also known as integrin beta-2, plays a key role in mediating interactions between immune cells and the surrounding environment. By binding to CD18, this antibody facilitates the visualization and analysis of the CD18 protein in various cell types.

It is particularly valuable for studies in immunology, inflammation, and autoimmune diseases.Understanding the function and regulation of CD18 is essential for unraveling the complexities of immune response and developing targeted therapies for conditions where immune cell interactions are dysregulated. The Human CD18 Monoclonal Antibody (Biotin Conjugated) TS1/18, 1/2/11 (AGEL0240) provides researchers with a precise tool to advance their investigations in these critical areas of study.

Product Title:Biotin Anti-Human CD18 Antibody [TS1/18.1.2.11]
SKU:AGEL0240
Size:25µg, 100µg
Clone No:TS1/18.1.2.11
Synonyms:Integrin beta-2;Itgb2;Cell surface adhesion glycoproteins LFA-1/CR3/p150+95 subunit beta;Complement receptor C3 subunit beta;CD18;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Biotin Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P05107
Gene ID:3689
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD18 is a 90-95 kD type I transmembrane protein also known as integrin β2 subunit, LFA-1 β subunit, and β2 integrin. CD18 non-covalently associates with CD11a, CD11b or CD11c. CD18 is expressed on all leukocytes. CD18 and associated α chains function in adhesion and signaling in hematopoietic cells.

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