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PE Anti-Human CD18 Antibody [TS1/18.1.2.11] (AGEL0242)

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SKU AGEL0242
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Human
Host Species Mouse
Isotype IgG1
Clone TS1/18.1.2.11
Conjugation PE
Applications FC
€98 - €390

Description

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PE Anti-Human CD18 Antibody [TS1/18.1.2.11]

The Human CD18 Monoclonal Antibody PE Conjugated (TS1/18) (AGEL0242) is a cutting-edge tool for researchers studying cell adhesion and inflammation mechanisms. This antibody, specifically targeting the CD18 protein, is conjugated with PE for flow cytometry applications, allowing for precise and efficient detection of CD18 expression in human samples.CD18, a subunit of the β2 integrin family, plays a crucial role in cell adhesion and migration processes essential for immune responses. By targeting CD18 with this monoclonal antibody, researchers can gain valuable insights into the mechanisms governing immune cell interactions and inflammatory pathways. This antibody is validated for use in flow cytometry, enabling accurate quantification of CD18 expression levels on various cell types, making it an invaluable tool for immunology and inflammation research.

Understanding the function and regulation of CD18 is fundamental for deciphering complex immunological processes and developing targeted therapies for inflammatory disorders, autoimmune diseases, and other conditions related to aberrant immune responses. The Human CD18 Monoclonal Antibody PE Conjugated (TS1/18) (AGEL0242) offers researchers a powerful tool to advance their studies and contribute to the growing body of knowledge in immunology and inflammation research.

Product Title:PE Anti-Human CD18 Antibody [TS1/18.1.2.11]
SKU:AGEL0242
Size:20 Tests, 100 Tests, 200 Tests
Clone No:TS1/18.1.2.11
Synonyms:Integrin beta-2;Itgb2;Cell surface adhesion glycoproteins LFA-1/CR3/p150+95 subunit beta;Complement receptor C3 subunit beta;CD18;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P05107
Gene ID:3689
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD18 is a 90-95 kD type I transmembrane protein also known as integrin β2 subunit, LFA-1 β subunit, and β2 integrin. CD18 non-covalently associates with CD11a, CD11b or CD11c. CD18 is expressed on all leukocytes. CD18 and associated α chains function in adhesion and signaling in hematopoietic cells.

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