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APC Anti-Human CD29 Antibody [TS2/16.2.1] (AGEL0216)

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SKU AGEL0216
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Human
Host Species Mouse
Isotype IgG1
Clone TS2/16.2.1
Conjugation APC
Applications FC
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Description

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APC Anti-Human CD29 Antibody [TS2/16.2.1]

The Human CD29 Monoclonal Antibody (APC Conjugated) TS2/16.2.1 (AGEL0216) is a cutting-edge tool designed for researchers studying CD29, a key cell surface protein involved in cell adhesion and migration processes. This monoclonal antibody, labeled with APC for enhanced detection, is specifically tailored for use in flow cytometry applications. It recognizes the CD29 protein with high specificity, facilitating precise identification and analysis of CD29 expression in human samples across various cell types.CD29, also known as integrin beta-1, plays a crucial role in cellular interactions with the extracellular matrix and other cells, influencing various physiological and pathological processes such as tissue development, wound healing, and cancer metastasis.

By targeting CD29, researchers can gain valuable insights into cell behavior, migration patterns, and signaling pathways, particularly in the fields of immunology, oncology, and regenerative medicine. Investigating CD29 expression and function can provide essential information for understanding disease mechanisms and developing innovative therapeutic strategies targeting cell adhesion and migration dynamics.

Product Title:APC Anti-Human CD29 Antibody [TS2/16.2.1]
SKU:AGEL0216
Size:20 Tests, 100 Tests, 200 Tests
Clone No:TS2/16.2.1
Synonyms:Integrin beta-1;ITB1;Itgb1;Fibronectin receptor subunit beta;VLA-4 subunit beta;CD29;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P05556
Gene ID:3688
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD29 is a 130 kD single chain type I glycoprotein also known as integrin β1, VLA-β chain, or gpIIa. It is broadly expressed on a majority of hematopoietic and non-hematopoietic cells, including leukocytes (although at low level on granulocytes), platelets, fibroblasts, endothelial cells, epithelial cells, and mast cells. CD29 is a member of the integrin family. It is non-covalently associated with integrin α1-α6 chains to form VLA-1 to VLA-6 molecules, respectively. Integrins, which include CD29, bind to several cell surface (e.g. VCAM-1, MadCAM-1) and extracellular matrix molecules. CD29 acts as a fibronectin receptor and is involved in a variety of cell-cell and cell-matrix interactions.

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