The Human CD29 Monoclonal Antibody (PERCP-Cyanine5.5 Conjugated) TS2/16 (AGEL0939) available from AssayGenie is a cutting-edge tool designed for researchers studying CD29, a vital cell surface integrin involved in cell adhesion and migration. This monoclonal antibody, conjugated with PERCP-Cyanine5.5, specifically targets human CD29 and is ideal for flow cytometry applications.CD29, also known as integrin beta-1, plays a crucial role in numerous cellular processes, including cell signaling, proliferation, and differentiation. It serves as a key mediator of interactions between cells and their extracellular matrices, making it essential for tissue development and maintenance. By targeting CD29, researchers can investigate mechanisms underlying cell behavior, tissue remodeling, and disease progression, particularly in the fields of cell biology and cancer research.
With its high specificity and validated performance in flow cytometry, the Human CD29 Monoclonal Antibody (PERCP-Cyanine5.5 Conjugated) TS2/16 (AGEL0939) offers researchers a powerful tool for exploring the functions and mechanisms of CD29 in various biological contexts. This antibody opens up new possibilities for in-depth studies on cell adhesion, migration, and integrin signaling pathways, paving the way for discoveries that may advance our understanding of cellular behavior and disease processes.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05556
Gene ID:
3688
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD29 is a 130 kD single chain type I glycoprotein also known as integrin β1, VLA-β chain, or gpIIa. It is broadly expressed on a majority of hematopoietic and non-hematopoietic cells, including leukocytes (although at low level on granulocytes), platelets, fibroblasts, endothelial cells, epithelial cells, and mast cells. CD29 is a member of the integrin family. It is non-covalently associated with integrin α1-α6 chains to form VLA-1 to VLA-6 molecules, respectively. Integrins, which include CD29, bind to several cell surface (e.g. VCAM-1, MadCAM-1) and extracellular matrix molecules. CD29 acts as a fibronectin receptor and is involved in a variety of cell-cell and cell-matrix interactions.
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