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Key Features

PE/Cyanine7 Anti-Human CD40 Antibody [G28.5] (AGEL2098)

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SKU AGEL2098
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Human
Host Species Mouse
Isotype IgG2a,k
Clone G28.5
Conjugation PE/Cy7
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Description

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PE/Cyanine7 Anti-Human CD40 Antibody [G28.5]

The Human CD40 Monoclonal Antibody (PE/Cyanine7 Conjugated) G28-5 (AGEL2098) is a powerful tool for researchers studying the CD40 protein, a key player in immune signaling pathways. This antibody, derived from a monoclonal source, exhibits high specificity and sensitivity for human CD40, making it an excellent choice for various experimental applications.CD40 is a cell surface receptor that regulates immune responses and plays a vital role in the activation of B cells and other immune cells. By targeting CD40, researchers can gain insight into immune system function, inflammation, and potential therapeutic targets for various diseases, including cancer and autoimmune disorders.

With its PE/Cyanine7 conjugation, this antibody enables robust detection and analysis of CD40 expression in flow cytometry and immunofluorescence experiments. Its versatility and reliability make it an indispensable tool for scientists exploring the intricacies of immune response modulation and potential treatment strategies in a variety of research settings.Invest in the Human CD40 Monoclonal Antibody (PE/Cyanine7 Conjugated) G28-5 (AGEL2098) to advance your research in immunology, oncology, and beyond.

Product Title:PE/Cyanine7 Anti-Human CD40 Antibody [G28.5]
SKU:AGEL2098
Size:20 Tests, 100 Tests, 200 Tests
Clone No:G28.5
Synonyms:Bp50;CDw40;CD40L receptor;TNFRSF5;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE/Cyanine7 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P25942
Gene ID:958
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand).

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