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APC Anti-Human CD41 Antibody [HIP8] (AGEL1132)

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SKU AGEL1132
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Human
Applications FC
€113 - €495
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Description

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APC Anti-Human CD41 Antibody [HIP8]

The Human CD41 Monoclonal Antibody (APC-conjugated, HIP8) is a cutting-edge tool for researchers involved in studying CD41, a crucial cell surface glycoprotein. This monoclonal antibody is specifically designed for high reactivity with human samples and is validated for use in flow cytometry applications. By binding to the CD41 antigen, it allows for precise detection and analysis in a variety of cell types, making it an invaluable asset for investigations in hematology, immunology, and related fields.

CD41, also known as integrin alpha IIb, plays a vital role in platelet aggregation, thrombosis, and hemostasis. Its involvement in these essential processes underscores its significance in understanding bleeding disorders, cardiovascular diseases, and thrombotic conditions. Researchers studying diseases related to platelet function and coagulation cascades will find this monoclonal antibody particularly useful in elucidating the mechanisms underlying these complex physiological pathways.

Product Title:APC Anti-Human CD41 Antibody [HIP8]
SKU:AGEL1132
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HIP8
Synonyms:Integrin alpha-Iib;ITGA2B;GPalpha Iib;GPIIb;Platelet membrane glycoprotein Iib;CD41;GP2B; ITGAB;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P08514
Gene ID:3674
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD41 is a 125/25 kD α subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbα) and light chain (gpIIbβ) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor and thrombin.

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