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PE Anti-Human CD41 Antibody [HIP8] (AGEL1131)

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SKU AGEL1131
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Human
Applications FC
€94 - €428
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Description

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PE Anti-Human CD41 Antibody [HIP8]

The Human CD41 Monoclonal Antibody (PE Conjugated, HIP8) is a cutting-edge tool for researchers studying CD41, a key protein involved in platelet aggregation and blood clotting processes. This monoclonal antibody, conjugated with phycoerythrin (PE), offers high specificity and sensitivity for detecting CD41 in human samples, making it a valuable asset for flow cytometry and immunofluorescence experiments.CD41, also known as integrin alpha IIb, is essential for platelet function and hemostasis, playing a crucial role in the formation of blood clots.

Dysregulation of CD41 can lead to bleeding disorders or thrombotic events, highlighting its clinical relevance in conditions such as thrombocytopenia, thrombosis, and cardiovascular diseases. By utilizing the Human CD41 Monoclonal Antibody (PE Conjugated, HIP8), researchers can gain insights into the expression and localization of CD41 in various cell types and tissues, advancing our understanding of platelet biology and related pathologies.

Product Title:PE Anti-Human CD41 Antibody [HIP8]
SKU:AGEL1131
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HIP8
Synonyms:Integrin alpha-Iib;ITGA2B;GPalpha Iib;GPIIb;Platelet membrane glycoprotein Iib;CD41;GP2B; ITGAB;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P08514
Gene ID:3674
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD41 is a 125/25 kD α subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbα) and light chain (gpIIbβ) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor and thrombin.

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