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PE Anti-Human CD45RO Antibody [UCHL1] (AGEL1697)

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SKU AGEL1697
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Human
Host Species Mouse
Isotype IgG2a,k
Clone UCHL1
Conjugation PE
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Description

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PE Anti-Human CD45RO Antibody [UCHL1]

The Human CD45RO Monoclonal Antibody (PE Conjugated, Clone UCHL1) is an essential tool for researchers studying immune cell subsets, particularly T lymphocytes. This antibody, available from AssayGenie (product code AGEL1697), specifically targets the CD45RO antigen found on memory T cells and activated T cells.CD45RO is a marker of antigen-experienced T cells, helping to differentiate them from naive T cells. This PE-conjugated monoclonal antibody, derived from the UCHL1 clone, allows for the detection and analysis of CD45RO-expressing cells using flow cytometry.

Its high reactivity with human samples ensures reliable and specific results in immunophenotyping studies.By targeting CD45RO, researchers can gain valuable insights into immune responses, memory T cell populations, and immune system dynamics in various health and disease states. Whether investigating immune memory formation, immune surveillance, or immune dysfunction, this CD45RO monoclonal antibody is a valuable tool for advancing immunological research.

Product Title:PE Anti-Human CD45RO Antibody [UCHL1]
SKU:AGEL1697
Size:20 Tests, 100 Tests, 200 Tests
Clone No:UCHL1
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:PE Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Gene ID:5788
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.

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