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PE Anti-Human CD57 Antibody [HNK-1] (AGEL0268)

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SKU AGEL0268
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Human
Host Species Mouse
Isotype IgM
Clone HNK-1
Conjugation PE
Applications FC
€100 - €390
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Description

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PE Anti-Human CD57 Antibody [HNK-1]

The Human CD57 Monoclonal Antibody (PE Conjugated) is a specialized antibody designed for research applications involving CD57, a cell surface marker associated with natural killer cells and certain T cell subsets. This PE-conjugated monoclonal antibody, known as HNK-1 (AGEL0268), is highly reactive with human samples and is suitable for flow cytometry analysis. It specifically binds to the CD57 antigen, enabling precise identification and characterization of CD57-expressing cells in a variety of biological samples.CD57, also referred to as HNK-1, is a marker commonly used to distinguish subsets of lymphocytes with specific immune functions.

Its presence on cell surfaces is indicative of certain immune responses and has been linked to various immune-related disorders and diseases. By utilizing the CD57 Monoclonal Antibody (PE Conjugated), researchers can delve deeper into the role of CD57-expressing cells in immunology, infectious diseases, cancer immunotherapy, and other biomedical research fields. Understanding the function and behavior of CD57-positive cells is vital for advancing our knowledge of immune responses and developing targeted therapeutic interventions.

Product Title:PE Anti-Human CD57 Antibody [HNK-1]
SKU:AGEL0268
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HNK-1
Synonyms:HNK-1; NK-1; Leu-7;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgM, κ
Isotype Control:PE Mouse IgM, κ Isotype Control[MM-30]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Gene ID:27087
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD57, also known as HNK-1, NK-1, and Leu-7 is a 100-115 kD oligosaccharide antigenic determinant expressed on a variety of proteins, lipids, and chondroitin sulfate proteoglycans. CD57 is expressed on a subset of peripheral blood lymphocytes, including NK cells and CD8+ T cells, and is also expressed on neural cells and striated muscle. CD57 is not expressed on red blood cells, granulocytes, monocytes, or platelets. While the function of CD57 is unknown, binding to L-selectin, P-selectin, and a fragment of laminin suggests that CD57 may be involved in cell-matrix interactions. CD57 is increased in some disease states associated with CD4/CD8 imbalances (AIDS, autoimmune disease, viral infections, and allograft transplants).

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