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APC Anti-Human CD86 Antibody [BU63] (AGEL0645)

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SKU AGEL0645
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Human
Host Species Mouse
Isotype IgG2a,k
Clone BU63
Conjugation APC
€113 - €495
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Description

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APC Anti-Human CD86 Antibody [BU63]

The Human CD86 Monoclonal Antibody (APC-conjugated, BU63, AGEL0645) offered by AssayGenie is a cutting-edge tool for researchers in the field of immunology. This antibody specifically targets the CD86 protein, a key surface molecule involved in immune responses and T cell activation. With high reactivity towards human samples, this monoclonal antibody is optimized for use in flow cytometry applications, enabling precise detection and analysis of CD86 expression in various cell types. The APC conjugation enhances signal intensity, allowing for reliable and sensitive measurements.CD86, also known as B7-2, plays a crucial role in T cell co-stimulation and immune regulation, making it a pivotal target for investigations related to autoimmune diseases, transplant rejection, and immune system dysregulation.

By understanding the function and expression of CD86, researchers can uncover potential therapeutic targets and develop innovative treatments for a range of immune-related disorders.Invest in the Human CD86 Monoclonal Antibody (APC-conjugated, BU63, AGEL0645) from AssayGenie to advance your research in immunology and unravel the complexities of immune response modulation.

Product Title:APC Anti-Human CD86 Antibody [BU63]
SKU:AGEL0645
Size:20 Tests, 100 Tests, 200 Tests
Clone No:BU63
Synonyms:T-lymphocyte activation antigen CD86;Cd86;Activation B7-2 antigen;Early T-cell costimulatory molecule 1;ETC-1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P42081
Gene ID:942
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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