Human CXCR4 Full-Length Bioactive Membrane Protein (HDFP055)
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- SKU:
- HDFP055
- Product Type:
- Recombinant Protein
- Protein Type:
- Full-Length Bioactive Membrane Protein
- Species:
- Human
- Uniprot:
- P61073
Description
system_update_altDatasheet
| Product name | Human CXCR4 full length protein-synthetic nanodisc |
| Size: | 10ug |
| Product SKU: | HDFP055 |
| Product Category | Full Length Transmembrane Proteins |
| Target: | CXCR4 |
| Uniprot: | P61073 |
| Description: | Human CXCR4 full length protein-synthetic nanodisc |
| Molecular Weight: | The human full length CXCR4 protein has a MW of 39.7 kDa |
| Protein Family: | Druggable Genome, ES Cell Differentiation/IPS, GPCR, Transmembrane |
| Protein Pathways: | Axon guidance, Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Endocytosis, Leukocyte transendothelial migration |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Synonyms: | CD184; D2S201E; FB22; HM89; HSY3RR; LAP-3; LAP3; LCR1; LESTR; NPY3R; NPYR; NPYRL; NPYY3R; WHIM; WHIMS |
| Expression System: | HEK293 |
| Formulation: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Background: | A CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. |
| Delivery: | In Stock |
| Usage | Research use only |
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