Description
| Product Name: | Nanodisc Human FSHR-Strep Protein |
| SKU: | HDFP789 |
| Size: | 10μg |
| Target: | FSHR |
| Tag: | C-Flag&Strep Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | FSHR1; FSHRO; LGR1; ODG1 |
| Protein Families: | Druggable Genome, ES Cell Differentiation/IPS, GPCR, Transmembrane. |
| Protein Description: | Human FSHR-Strep full length protein-synthetic nanodisc |
| Protein Pathways: | Neuroactive ligand-receptor interaction. |
| Molecular Weight: | The human full length FSHR-Strep protein has a MW of 78.3 kDa |
The protein belongs to family 1 of G-protein coupled receptors. It is the receptor for follicle stimulating hormone and functions in gonad development. Mutations in this gene cause ovarian dysgenesis type 1, and also ovarian hyperstimulation syndrome. Alternative splicing results in multiple transcript variants.
| Uniprot ID: | P23945 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
