Description
system_update_altDatasheet
| Product name | Human GPR77 full length protein-synthetic nanodisc |
| Size: | 10ug |
| Product SKU: | HDFP050 |
| Product Category | Full Length Transmembrane Proteins |
| Target: | C5AR2 |
| Uniprot: | Q9P296 |
| Description: | Human GPR77 full length protein-synthetic nanodisc |
| Molecular Weight: | The human full length C5AR2 protein has a MW of 36.1 kDa |
| Protein Family: | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways: | |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Synonyms: | C5L2; GPF77; GPR77 |
| Expression System: | HEK293 |
| Formulation: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Background: | This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012] |
| Delivery: | 3-4 weeks |
| Usage | Research use only |
