Description
Product Name: | Nanodisc Human GRIA1 Protein |
SKU: | HDFP747 |
Size: | 10μg |
Target: | GRIA1 |
Tag: | C-Flag Tag |
Expression Host: | HEK293 |
Conjugate: | Unconjugated |
Synonyms: | GLUH1, GLUR1, GLURA, GluA1, HBGR1 |
Protein Families: | Ion Channels: Glutamate Receptors. |
Protein Description: | Human GRIA1 full length protein-synthetic nanodisc |
Molecular Weight: | The human full length GRIA1 protein has a MW of 101.5kDa |
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot ID: | P42261 |
Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Usage: | Research use only |