Description
| Product Name: | Nanodisc Human HCRTR1-Strep Protein |
| SKU: | HDFP835 |
| Size: | 10μg |
| Target: | HCRTR1 |
| Tag: | C-Flag&Strep Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | ORXR1;OX1R;OXR1 |
| Protein Families: | Druggable Genome, ES Cell Differentiation/IPS, GPCR, Transmembrane. |
| Protein Description: | Human HCRTR1-Strep full length protein-synthetic nanodisc |
| Protein Pathways: | Neuroactive ligand-receptor interaction. |
| Molecular Weight: | The human full length HCRTR1-Strep protein has a MW of 47.5 kDa |
The protein is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B.
| Uniprot ID: | O43613 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
