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GenieFluor 647 Anti-Human HLA-A,B,C Antibody [W6/32] (AGEL1623)

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SKU AGEL1623
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Human
Host Species Mouse
Isotype IgG2a,k
Clone W6/32
Conjugation AF 647
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Description

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GenieFluor 647 Anti-Human HLA-A,B,C Antibody [W6/32]

The Human HLA-A/B/C Monoclonal Antibody (AF647 Conjugated) W6/32 (AGEL1623) is a powerful tool for immunology and histocompatibility research. This monoclonal antibody, conjugated to the Alexa Fluor 647 fluorophore, specifically targets the HLA-A, HLA-B, and HLA-C proteins, which are key components of the human major histocompatibility complex (MHC).HLA molecules play a crucial role in immune response by presenting antigens to T cells, triggering immune reactions against pathogens or abnormal cells. The W6/32 antibody, known for its high specificity and sensitivity, enables precise detection and visualization of HLA-A/B/C molecules in various experimental settings, such as flow cytometry, immunofluorescence, and immunohistochemistry.

By using the HLA-A/B/C Monoclonal Antibody AF647 Conjugated W6/32 (AGEL1623), researchers can explore the complex interactions between MHC molecules and immune cells. This antibody is an invaluable tool for studying antigen presentation, T cell recognition, and immune system function in health and disease, including infectious diseases, autoimmune disorders, and transplant immunology. Its applications extend to basic research, drug development, and diagnostic assays aimed at understanding and manipulating immune responses for therapeutic purposes.

Product Title:GenieFluor 647 Anti-Human HLA-A,B,C Antibody [W6/32]
SKU:AGEL1623
Size:20 Tests, 100 Tests, 200 Tests
Clone No:W6/32
Synonyms:Major Histocompatibility Class I; MHC class I;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:Genie Fluor 647 Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P04439 P01889 P10321
Gene ID:3105
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:MHC class I antigens associated with β2-microglobulin are expressed by all human nucleated cells. MHC class I molecules are involved in presentation of antigens to CD8+ T cells. They play an important role in cell-mediated immune responses and tumor surveillance.

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