The Human HLA-A/B/C Monoclonal Antibody (Biotin Conjugated) W6/32 (AGEL1613) is a powerful tool for researchers studying human histocompatibility antigens and immune responses. This monoclonal antibody, conjugated with biotin for enhanced detection capabilities, specifically targets the HLA-A, HLA-B, and HLA-C proteins. By utilizing the W6/32 antibody, researchers can accurately detect and analyze these crucial histocompatibility molecules in various biological samples.HLA molecules play a crucial role in presenting antigens to the immune system, thereby influencing immune responses and contributing to the body's defense mechanisms.
The W6/32 antibody is particularly valuable for investigations in immunology, transplantation, and infectious diseases, where understanding HLA expression and function is paramount.By utilizing the Human HLA-A/B/C Monoclonal Antibody (Biotin Conjugated) W6/32 (AGEL1613), researchers gain a reliable tool to study the complexities of human histocompatibility antigens, paving the way for advancements in personalized medicine, immunotherapy, and the treatment of various diseases.
Product Title:
Biotin Anti-Human HLA-A,B,C Antibody [W6/32]
SKU:
AGEL1613
Size:
25µg, 100µg
Clone No:
W6/32
Synonyms:
Major Histocompatibility Class I; MHC class I;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG2a, κ
Isotype Control:
Biotin Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:
Liquid
Conjugation:
Biotin
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:
P04439 P01889 P10321
Gene ID:
3105
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
MHC class I antigens associated with β2-microglobulin are expressed by all human nucleated cells. MHC class I molecules are involved in presentation of antigens to CD8+ T cells. They play an important role in cell-mediated immune responses and tumor surveillance.
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