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PE Anti-Human HLA-DR Antibody [L243] (AGEL0416)

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SKU AGEL0416
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Human
Host Species Mouse
Isotype IgG2a
Clone L243
Conjugation PE
Applications FC
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Description

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PE Anti-Human HLA-DR Antibody [L243]

The HLA-DR Monoclonal Antibody (PE Conjugated) L243 (AGel0416) is a powerful tool for immunological research, targeting the human leukocyte antigen HLA-DR. This monoclonal antibody, conjugated with the fluorescent dye PE (phycoerythrin), offers researchers an efficient means of detecting and analyzing HLA-DR expression in various cell types.HLA-DR is a crucial component of the human immune system, playing a key role in antigen presentation to T-cells and initiating adaptive immune responses. The L243 antibody specifically recognizes the HLA-DR protein, allowing for precise detection and characterization of HLA-DR-expressing cells in immunological studies.This antibody is ideal for applications such as flow cytometry, immunofluorescence, and immunohistochemistry, enabling researchers to investigate the role of HLA-DR in immune responses, autoimmune diseases, transplantation, and infectious diseases.

Its high specificity and sensitivity make it a valuable tool for gaining insights into the complex mechanisms of the human immune system.Whether studying basic immunology, cell biology, or clinical research, the HLA-DR Monoclonal Antibody (PE Conjugated) L243 (AGel0416) offers reliable performance and accurate results, making it a valuable asset for advancing our understanding of immune processes and developing potential therapeutic interventions.

Product Title:PE Anti-Human HLA-DR Antibody [L243]
SKU:AGEL0416
Size:20 Tests, 100 Tests, 200 Tests
Clone No:L243
Synonyms:HLA class II histocompatibility antigen DR alpha/ DRB1-15 beta chain;MHC class II antigen DRA;HLA-DRA1/DRB1;DRA/DRB1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:PE Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P01903 P01911
Gene ID:3122,3123
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells.

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