Description
system_update_altDatasheet
| Product name | Human HRH3 full length protein-synthetic nanodisc |
| Size: | 10ug |
| Product SKU: | HDFP114 |
| Product Category | Full Length Transmembrane Proteins |
| Target: | HRH3 |
| Uniprot: | Q9Y5N1 |
| Description: | Human HRH3 full length protein-synthetic nanodisc |
| Molecular Weight: | The human full length HRH3 protein has a MW of 48.5 kDa |
| Protein Family: | Druggable Genome, Transmembrane |
| Protein Pathways: | Neuroactive ligand-receptor interaction |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Synonyms: | GPCR97; HH3R |
| Expression System: | HEK293 |
| Formulation: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Background: | Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system. [provided by RefSeq, Jul 2008] |
| Delivery: | 3-4 weeks |
| Usage | Research use only |
