Description
| Product Name: | Nanodisc Human HRH4-Strep Protein |
| SKU: | HDFP1056 |
| Size: | 10μg |
| Target: | HRH4 |
| Tag: | C-Flag&Strep Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | AXOR35, BG26, GPCR105, GPRv53, H4, H4R, HH4R |
| Protein Families: | GPCR, Transmembrane, Druggable Genome. |
| Protein Description: | Human HRH4-Strep full length protein-synthetic nanodisc |
| Protein Pathways: | GPCRDB Other, Cancer. |
| Molecular Weight: | The human full length HRH4-Strep protein has a MW of 44.5 kDa |
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. This gene encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The protein is thought to play a role in inflammation and allergy reponses. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
| Uniprot ID: | Q9H3N8 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
