Description
| Product Name: | Human LSM12 Recombinant Protein |
| Product Code: | RPPB3882 |
| Size: | 10µg |
| Species: | Human |
| Target: | LSM12 |
| Synonyms: | PNAS-135, Protein LSM12 homolog, LSM12. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | LSM12 protein solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 7.5), 0.1M NaCl, 10% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMAAPPGE YFSVGSQVSC RTCQEQRLQG EVVAFDYQSK MLALKCPSSS GKPNHADILL INLQYVSEVE IINDRTETPP PLASLNVSKL ASKARTEKEE KLSQAYAISA GVSLEGQQLF QTIHKTIKDC KWQEKNIVVM EEVVITPPYQ VENCKGKEGS ALSHVRKIVE KHFRDVESQK ILQRSQAQQP QKEAALSS |
LSM12 Homolog, U6 Small Nuclear RNA Associated (LSM12) is a member of the snRNP Sm proteins family. Sm-like proteins were detected in various organisms based on sequence homology with the Sm protein family. Sm-like proteins comprise the Sm sequence motif, which consists of two regions parted by a linker of variable length which folds as a loop. The Sm-like proteins are assumed to create a stable heteromer present in tri-snRNP particles, which are significant for pre-mRNA splicing.
LSM12 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 218 amino acids (1-195 a.a.) and having a molecular mass of 24.1kDa.LSM12 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | LSM12: Belongs to the LSM12 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 17q21.31 |
| UniProt Code: | Q3MHD2 |
| NCBI GenInfo Identifier: | 158705881 |
| NCBI Gene ID: | 124801 |
| NCBI Accession: | Q3MHD2.2 |
| UniProt Secondary Accession: | Q3MHD2,Q86YB1, Q96NL5, |
| UniProt Related Accession: | Q3MHD2 |
| Molecular Weight: | 21,999 Da |
| NCBI Full Name: | Protein LSM12 homolog |
| NCBI Synonym Full Names: | LSM12 homolog |
| NCBI Official Symbol: | LSM12�� |
| NCBI Official Synonym Symbols: | PNAS-135�� |
| NCBI Protein Information: | protein LSM12 homolog |
| UniProt Protein Name: | Protein LSM12 homolog |
| Protein Family: | Protein |
| UniProt Gene Name: | LSM12�� |
| UniProt Entry Name: | LSM12_HUMAN |
