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FITC Anti-Human/Mouse/Rat CD47 Antibody [MIAP410] (AGEL0679)

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SKU AGEL0679
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Human
Reactivity Mouse
Reactivity Rat
Host Species Mouse
Isotype IgG2a,k
Clone MIAP410
Conjugation FITC
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Description

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FITC Anti-Human/Mouse/Rat CD47 Antibody [MIAP410]

The CD47 Monoclonal Antibody (AGEL0679) offered by Assay Genie is a powerful tool for researchers studying CD47, a cell surface protein with diverse functions in immune regulation and cancer biology. This FITC-conjugated antibody specifically targets CD47 in human, mouse, and rat samples, providing reliable detection and analysis across species.CD47, also known as integrin-associated protein, plays a key role in immune evasion and cell signaling processes. Its overexpression is often associated with the ability of cancer cells to evade detection and destruction by the immune system. By targeting CD47 with this monoclonal antibody, researchers can investigate its role in immune responses, tumor development, and therapeutic resistance.

Validated for various applications such as flow cytometry and immunofluorescence, this CD47 monoclonal antibody is a valuable tool for studies in immunology, oncology, and drug development. By enabling precise visualization and quantification of CD47 expression in different cell types and tissues, researchers can gain insights into the mechanisms underlying immune evasion and tumor progression. Unlock the potential of your research with the CD47 Monoclonal Antibody from Assay Genie.

Product Title:FITC Anti-Human/Mouse/Rat CD47 Antibody [MIAP410]
SKU:AGEL0679
Size:25µg, 100µg
Clone No:MIAP410
Synonyms:Leukocyte surface antigen CD47;Cd47;Integrin-associated protein;IAP;
Host Species:Mouse
Reactivity:Human;Mouse;Rat
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q08722 Q61735 P97829
Gene ID:961,16423,29364
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.

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