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PerCP/Cyanine5.5 Anti-Human/Mouse/Rat CD47 Antibody [MIAP410] (AGEL0676)

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SKU AGEL0676
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Human
Reactivity Mouse
Reactivity Rat
Host Species Mouse
Isotype IgG2a,k
Clone MIAP410
Conjugation PerCP/Cy5.5
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Description

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PerCP/Cyanine5.5 Anti-Human/Mouse/Rat CD47 Antibody [MIAP410]

The CD47 Monoclonal Antibody (PERCP/Cyanine5.5 Conjugated, MIAP410) from Assay Genie (AGEL0676) is a high-quality antibody designed for research involving CD47, a widely studied cell surface protein known for its role in immune regulation and evasion of immune responses. This monoclonal antibody is developed for use in flow cytometry applications, enabling precise detection and analysis of CD47 expression on human, mouse, and rat cells.CD47, also known as integrin-associated protein, is a key player in immune signaling and modulation of phagocytosis. Its interaction with SIRP-alpha on macrophages serves as a "don't eat me" signal, allowing cancer cells and other target cells to evade immune clearance. The CD47 Monoclonal Antibody offered by Assay Genie provides researchers with a reliable tool to investigate the expression and function of CD47 in various biological contexts, including immunology, oncology, and stem cell research.

By targeting CD47, researchers can gain insights into mechanisms of immune evasion and develop novel therapeutic strategies for cancer immunotherapy and other immune-related disorders. The conjugated format of this antibody allows for multi-color flow cytometry analysis, enhancing the versatility and precision of experimental workflows. Trust in the quality and specificity of the CD47 Monoclonal Antibody from Assay Genie to advance your research in the field of immune regulation and cellular interactions.

Product Title:PerCP/Cyanine5.5 Anti-Human/Mouse/Rat CD47 Antibody [MIAP410]
SKU:AGEL0676
Size:20 Tests, 100 Tests, 200 Tests
Clone No:MIAP410
Synonyms:Leukocyte surface antigen CD47;Cd47;Integrin-associated protein;IAP;
Host Species:Mouse
Reactivity:Human;Mouse;Rat
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PerCP/Cyanine5.5 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q08722 Q61735 P97829
Gene ID:961,16423,29364
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.

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